Kūʻai iā Croda no kāna kuleana nui i nā lāʻau āpau Covid mRNA

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ʻO Croda International (CRDA), ka hui kemika o UK, like me kahi waihona ʻoihana lepo - ʻaʻole pīhoihoi nui akā ʻo ka mea loaʻa mau a me ka uku o nā uku. ʻĀpono ʻo Croda e uku i ka uku, ʻoiai me ka loaʻa haʻahaʻa o 1.7% a kūlike ka loaʻa a loaʻa ke wānana ʻia, a ke piʻi nei i luna no nā makahiki i hala.

Akā ʻo ka mea e kau ka maka e pili ana iā Croda kāna pivot i nā ʻepekema ola, me kēlā ʻāpana o nā ʻoihana o ka ʻoihana e lawe nei i ke ʻano nui ʻoi loa o ka hopena, kahi i puka mai ai ka ʻoihana ma ke ʻano he mea hoʻolako koʻikoʻi i nā mea hoʻohui no nā lāʻau āpau, ʻo ia hoʻi ka mRNA (messenger RNA ) nā mea i hoʻokumu ʻia e kaua iā Covid-19.

Ma hope o ka hana ʻelima mau makahiki me Pfizer i hoʻi mai i Nowemapa i ka makahiki i hala e hāʻawi i ʻehā mau mea hoʻohui lāʻau, i ʻike ʻia ma ke ʻano he poʻe lawe kālā, ua lawe ʻia ke kumukūʻai ma kahi hoʻolimalima hou o ke ola.

ʻO nā mea loaʻa ka mea hana ʻole i nā lāʻau lapaʻau a lilo i ka waena a kaʻa paha no ka lawe ʻana i ka mea hana i nā ʻāpana o ke kino kahi e pono ai.

Hoʻomaopopo ʻo Croda i ka ʻaelike me Pfizer ma kahi o $ 100 miliona i kēia makahiki wale nō ma ke kumu o Pfizer e hāʻawi ana iā 1.3 biliona Covid vaccine i ka 2021.

Eia kekahi, ʻo kā Croda's excipients me kahi wahi hou o ka lāʻau i kapa ʻia he lipop nanoparticles paʻa (SLNs) a i ʻole lipid nanoparticles (LNPs), a ua ʻenekini ʻia lākou e hiki ai i nā lāʻau āpau ke komo i nā pūnaewele. Ua ʻae ʻia kēia ala hou i ka formulate no ka hoʻohana ma 2018.

Noho ʻo Lipid nanoparticles i kahi kūlana paʻa ma ka lumi a me ka mahana o ke kino - ʻo lākou nā hale kūkulu o ke kūkulu ʻana o ka pūnaewele a hoʻopili pū me nā mea e like me nā momona a me nā aila. Loaʻa nā hunaahi i ka nui mai 50 a 1000 nm. No ka manaʻo o ka liʻiliʻi o nā nanoparticle, hoʻokahi nanometer like me 0.0000001 millimeter.

Māhele ʻo Croda ma kahi ʻōwili

Ua lele aku nā mahele o ka ʻoihana kemika hana kūikawā 10% i Nowemapa ma ka nūhou o ka lanakila Ptrizer

Pale nā ​​nanoparticle i ka ingredent ʻeleu mai, ma kekahi ʻaoʻao, e luku ʻia e ke kino i ke komo ʻana a ma ka ʻaoʻao ʻē aʻe e hiki ai i ka lāʻau ke komo i nā pūnaeho ola, no laila nā mea nui o ka hanauna lāʻau hou.

Ke lilo nei ka mea nui i ka ʻoihana lāʻau ʻo RNA (a me DNA) i ka ʻoihana lāʻau, me ka hopena maikaʻi o nā lāʻau mRNA no Covid ke kumu hoʻohālikelike maikaʻi loa a hiki i kēia lā. ʻAʻole nui nā mea pāʻani i ka papa SLN / LNP a ʻo Croda kekahi o nā mea hana nui loa.

ʻAʻole like me nā mea kūʻai aku kuʻuna, ʻoi aku ka nui o ka paʻakikī e pili ana i ka hana hoʻohuihui a me nā wahi e like me ka kānana a me ka paʻa. ʻO ia kekahi mau kumu no ka mea i holo ʻole ai nā mea hana lāʻau e hoʻohana i nā LNP, akā me nā lāʻau lapaʻau mRNA, RNA a me siRNA i paʻakikī loa, ʻaʻohe koho ʻē aʻe. ʻO ka kūleʻa o nā lāʻau āpau ʻo Pfizer-Biontech a me Moderna's Covid i wehe ākea i ka māla.

I kēia manawa he 12 mau moho wailele mRNA i kēia manawa a i ʻole i ka hoʻomohala ʻana a i ʻole i ka pae hoʻokolohua hoʻokolohua, e like me ka World Health Organization.

Mai ka manaʻo o ka mea hoʻopukapuka i kēlā manawa, aia kahi ala nui o Croda o ka ulu mua ma mua o ia, kahi e hōʻoia ai i kāna loiloi kiʻekiʻe e like me ke ana ʻia e kāna kumukūʻai i ka loaʻa kālā o 37.5; a ma hope o kāna mahina ʻo Nowemapa e kūʻai ana i ka 1.4% ma luna o ka pahuhopu kūkā ʻikepili a ka mea hoʻopukapuka o 6476p - i ka manawa e kākau ai ua uku ʻia nā ʻāpana Croda ma 6655p, a i 1.3% i kēia lā.

Ke ʻimi nei i nā hopena hopena o ka hui i 31 Kekemapa 2020, ua hoʻonui ka loaʻa kālā i kahi 1% a hiki i ka £ 1.39 biliona, ʻoiai loaʻa ka loaʻa kālā 10% i ka £ 201 miliona.

Eia nō naʻe, hūnā kēlā mau helu i ka hāʻawi i hāʻawi ʻia e ka ʻāpana Life Science, ka mea i hoʻonui i nā loaʻa e 15% a i ka £ 401 miliona.

Ua huki nui ʻia ka loaʻa kālā e ka ʻohana ʻoihana Pilikino, kahi i hoʻopaʻa inoa ʻia i ka hāʻule ʻana o 16% a i ka £ 136 miliona.

Ua hāʻule ka loaʻa kālā ma mua o ka ʻauhau i £ 269 miliona a me £ 302.3 miliona i kēlā me kēia makahiki, ʻoiai he 171p ka uku no kēlā me kēia mahele a wānana ʻia ma 2020p i kēia makahiki a 200p ma 221.

Loaʻa ka lanakila o Croda's LNP ma hope o ka loaʻa ʻana o Avanti a me Iberchem i ka makahiki i hala e pili ana i ka huikau o ka hōʻaiʻē a me ke kau pono ʻana. ʻO nā ʻalani Sepania a me nā mea ʻono Iberchem (kūʻai ʻia no 736 miliona) bolsters ʻo Croda i hiki ke hana a he alakaʻi ʻo Avanti i ka lawe lāʻau ʻana me ka hoʻohana ʻana i nā nanoparticle.

ʻO nā mea i loaʻa he ʻāpana o kā ka luna hoʻomalu i koi ʻia o ka 'hoʻohana ʻana i ka ʻepekema akamai e hoʻomaikaʻi i ke ola' a hoʻonohonoho i ka ʻoihana i mea pāʻani nui i ka wā e hiki mai ana o ka lawe lāʻau ʻana.

Kūʻai ikaika ʻo Croda.

Hiki iā ʻoe ke kūʻai iā Croda no ke komisina 0% ma ka paepae hoʻokele waiwai honua eToro.